| Singles competition |
| 1. #46 Brooke Despriet (SEWANEE) def. #45 Tessa Trate (CNUW) 6-2, 6-4 |
| 2. Alice Hall (SEWANEE) def. Raine Weis (CNUW) 6-3, 7-5 |
| 3. Emma Smith (SEWANEE) def. Kiersten Chang (CNUW) 6-2, 6-1 |
| 4. Sarah Livingston (SEWANEE) def. Karina Crivtonencu (CNUW) 6-1, 6-0 |
| 5. Natalia Nassar (SEWANEE) def. Kendra Womack (CNUW) 6-2, 6-1 |
| 6. Caroline Adams (SEWANEE) def. Megan Bauer (CNUW) 6-0, 6-1 |
| Doubles competition |
| 1. Brooke Despriet/Alice Hall (SEWANEE) def. Tessa Trate/Raine Weis (CNUW) 8-4 |
| 2. Ansley Carpenter/Natalia Nassar (SEWANEE) def. Kiersten Chang/Kendra Womack (CNUW) 8-2 |
| 3. Sarah Livingston/Nicole Nowak (SEWANEE) def. Anna Campbell/Amanda Yermal (CNUW) 8-3 |
| Match Notes |
| Chris. Newport 1-3 |
| Sewanee 2-0 |
| Sewanee finished No. 6 in the final 2021 ITA Division III national poll. |
| Chris. Newport finished No. 24 in the final 2021 ITA Division III national poll. |
| Match played at Washington and Lee University |